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Antigenic Specificity | PABPN1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: PABPN1 antibody detects endogenous levels of total PABPN1. Function: Involved in the 3'-end formation of mRNA precursors (pre-mRNA) by the addition of a poly(A) tail of 200-250 nt to the upstream cleavage product (By similarity). Stimulates poly(A) polymerase (PAPOLA) conferring processivity on the poly(A) tail elongation reaction and controls also the poly(A) tail length (By similarity). Increases the affinity of poly(A) polymerase for RNA (By similarity). Is also present at various stages of mRNA metabolism including nucleocytoplasmic trafficking and nonsense-mediated decay (NMD) of mRNA. Cooperates with SKIP to synergistically activate E-box-mediated transcription through MYOD1 and may regulate the expression of muscle-speci |
Immunogen | Immunogen: A synthesized peptide derived from human PABPN1 Subcellular Location: Nucleus Tissue Specificity: Ubiquitous. Predicted Cross Reactivity: Pig, Bovine, Horse, Rabbit, Dog Similarity: Pig (100%), Bovine (100%), Horse (100%), Rabbit (100%), Dog (100%) |
Other Names | [Nuclear poly(A)-binding protein 1; OPMD; PAB2; PABII; PABP 2; pABP-2; PABP2; PABP2_HUMAN; PABPII; Pabpn1; poly(A) binding protein nuclear 1; Poly(A)-binding protein 2; Poly(A)-binding protein II; PolyA binding protein II; Polyadenylate-binding nuclear protein 1; Polyadenylate-binding protein 2] |
Gene, Accession # | [PABPN1], Gene ID: 8106, NCBI: NP_004634.1, UniProt: Q86U42 |
Catalog # | MBS9608381 |
Price | $240, $280 |
Order / More Info | PABPN1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |