Edit |   |
---|---|
Antigenic Specificity | alpha-Synuclein |
Clone | polyclonal |
Host Species | Mouse |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | Protein A purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Alternatively spliced transcripts encoding different isoforms have been identified for this gene. |
Immunogen | Immunogen: Synuclein, alpha (non A4 component of amyloid precursor) |
Other Names | [Alpha synuclein; NACP; PARK1; PARK4; SNCA] |
Gene, Accession # | Gene ID: 6622, NCBI: NP_000336.1, UniProt: P37840 |
Catalog # | MBS7607412 |
Price | $265 |
Order / More Info | alpha-Synuclein Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |