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Antigenic Specificity | HP1gamma |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin, ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: HP1gamma Polyclonal Antibody detects endogenous levels of HP1gamma protein. At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. The chromobox 3 encoded by CBX3 binds DNA and is a component of heterochromatin. This protein also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane. This protein binds histone H3 tails methylated at Lys-9 sites. This protein is also recruited to sites of ultraviolet-induced DNA damage and double-strand breaks. Two transcript variants encoding the same protein but differing in t |
Immunogen | Immunogen: Synthesized peptide derived from human HP1gamma around the non-phosphorylation site of S93 |
Other Names | [Rabbit HP1gamma; CBX3; Chromobox protein homolog 3; HECH; Heterochromatin protein 1 homolog gamma; HP1 gamma; Modifier 2 protein] |
Gene, Accession # | [HP1gamma], Gene ID: 11335, NCBI: NP_009207.2, UniProt: Q13185 |
Catalog # | MBS9704283 |
Price | $130, $220, $325 |
Order / More Info | HP1gamma Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |