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Antigenic Specificity | FOXL2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | Protein G purified |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Transcriptional regulator. Critical factor essential for ovary differentiation and maintenance, and repression of the genetic program for somatic testis determination. Prevents trans-differentiation of ovary to testis through transcriptional repression of the Sertoli cell-promoting gene SOX9 (By similarity). Has apoptotic activity in ovarian cells. Suppresses ESR1-mediated transcription of PTGS2/COX2 stimulated by tamoxifen (By similarity). Is a regulator of CYP19 expression (By similarity). Participates in SMAD3-dependent transcription of FST via the intronic SMAD-binding element (By similarity). Is a transcriptional repressor of STAR. Activates SIRT1 transcription under cellular stress conditions. Activates transcription of OSR2. |
Immunogen | Immunogen: Recombinant Human Forkhead box protein L2 protein (116-216AA) |
Other Names | [Forkhead box protein L2; FOXL2] |
Gene, Accession # | [FOXL2], Gene ID: 668, NCBI: NP_075555.1, UniProt: P58012 |
Catalog # | MBS7107879 |
Price | $160, $235 |
Order / More Info | FOXL2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |