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Antigenic Specificity | GJA1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Western blot analysis of extracts of HeLa cell lines, using GJA1 antibody. Connexin 43 (Cx43) is a member of the large family of gap junction proteins. Connexins assemble as a hexamer and are transported to the plasma membrane to create a hemichannel that can associate with hemichannels on nearby cells to create cell-to-cell channels. Clusters of these channels assemble to make gap junctions. Gap junction communication is important in development and regulation of cell growth. Phosphorylation of Cx43 is important in regulating assembly and function of gap junctions (1, 2). Ser368 of Cx43 is phosphorylated by protein kinase C (PKC) after activation by phorbol esters, which decreases cell-to-cell communication (3). Src can intera |
Immunogen | Immunogen: Recombinant protein of human GJA1 |
Other Names | [GJA1, partial; Gap junction alpha-1 protein; gap junction alpha-1 protein; gap junction protein alpha 1; Connexin-43; Cx43; Gap junction 43 kDa heart protein] |
Gene, Accession # | [GJA1], Gene ID: 2697, NCBI: CAG46461.1 |
Catalog # | MBS4150020 |
Price | $385 |
Order / More Info | GJA1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |