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Antigenic Specificity | FBL - N-terminal region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | cow, dog, guinea pig, horse, human, mouse, rabbit, rat |
Isotype | n/a |
Format | Protein A purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Immunohistochemistry (IHC), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This is a rabbit polyclonal antibody against FBL. It was validated on Western Blot and immunohistochemistryTarget Description: FBL is a component of a nucleolar small nuclear ribonucleoprotein (snRNP) particle thought to participate in the first step in processing preribosomal RNA. It is associated with the U3, U8, and U13 small nuclear RNAs and is located in the dense fibrillar component (DFC) of the nucleolus. FBL contains an N-terminal repetitive domain that is rich in glycine and arginine residues, like fibrillarins in other species. Its central region resembles an RNA-binding domain and contains an RNP consensus sequence. Antisera from approximately 8% of humans with the autoimmune disease scleroderma recognize fibrillarin.This |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human FBL |
Other Names | [rRNA 2'-O-methyltransferase fibrillarin; rRNA 2'-O-methyltransferase fibrillarin; rRNA 2'-O-methyltransferase fibrillarin; fibrillarin; 34 kDa nucleolar scleroderma antigen] |
Gene, Accession # | [FBL], Gene ID: 2091, NCBI: NP_001427, UniProt: P22087 |
Catalog # | MBS3205175 |
Price | $290 |
Order / More Info | FBL - N-terminal region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |