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Antigenic Specificity | MARCH8 - middle region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | cow, dog, guinea pig, horse, human, mouse, rabbit, rat, zebrafish |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This is a rabbit polyclonal antibody against MARCH8. It was validated on Western Blot using a cell lysate as a positive control.Target Description: MARCH8 is an E3 ubiquitin-protein ligase that may regulate immune responses by promoting ubiquitination of MHC-II and CD86, which leads to their subsequent endocytosis and lysosomal degradation. It may also promote ubiquitination and endocytosis of TFRC and FAS. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates. |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human MARCH8 |
Other Names | [E3 ubiquitin-protein ligase MARCH8 isoform a; E3 ubiquitin-protein ligase MARCH8; E3 ubiquitin-protein ligase MARCH8; membrane associated ring-CH-type finger 8; Cellular modulator of immune recognition; c-MIR; Membrane-associated RING finger protein 8; Membrane-associated RING-CH protein VIII; MARCH-VIII; RING finger protein 178] |
Gene, Accession # | [MARCH8], Gene ID: 220972, NCBI: NP_659458, UniProt: Q5T0T0 |
Catalog # | MBS3206851 |
Price | $335 |
Order / More Info | MARCH8 - middle region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |