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Antigenic Specificity | DUSP14 (C-term), 168-198 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 2 |
Applications | Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This DUSP14 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 168-198 amino acids from the C-terminal region of human DUSP14. DUSP14 is involved in the inactivation of MAP kinases. This proein dephosphorylates ERK, JNK and p38 MAP-kinases. In addition to antigen recognition by the T-cell receptor, T-cell activation requires a second signal from a costimulatory receptor, such as CD28, which interacts with B7-1 (CD80) and B7-2 (CD86) ligands on antigen-presenting cells. CD28 costimulation induces transcription of interleukin-2 and stabilizes newly synthesized IL2 through the activation of mitogen-activated protein kinases (MAPKs), such as ERK and JNK, and the subsequent creation of AP1 transcription |
Immunogen | n/a |
Other Names | [Dual specificity protein phosphatase 14; MKP-1-like protein tyrosine phosphatase; MKP-L; Mitogen-activated protein kinase phosphatase 6; MAP kinase phosphatase 6; MKP-6; DUSP14; MKP6] |
Gene, Accession # | [DUSP14], Gene ID: 11072, NCBI: NP_008957.1, UniProt: O95147 |
Catalog # | MBS9210962 |
Price | $165, $370 |
Order / More Info | DUSP14 (C-term), 168-198 Antibody from MYBIOSOURCE INC. |
Product Specific References | Marti, F., et al., J. Immunol. 166(1):197-206 (2001). |