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Antigenic Specificity | Estrogen Receptor- beta |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | n/a |
Isotype | IgG2b kappa |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | Immunoblot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Anti-Estrogen Receptor beta [Murine MAb to fusion protein corresponding to aa 1-153 of human estrogen receptor-beta, a member of the steroid family of nuclear receptors.]. This antibody recognizes human ER- beta , a novel receptor (approx. 52 kD) recently isolated from testis. The size and structure of ER- beta are very similar to ER- alpha with the ligand and DNA binding domains being highly conserved. The N-terminus of each receptor, which serves as their transactivation domain, are significantly different. Like ER- alpha , ER- beta binds to estrogen with a high affinity and regulates estrogen-specific gene activation through direct interaction with estrogen response elements. |
Immunogen | Antigen: 6-His fusion protein containing the region encoding aa 1-153of human estrogen receptor- beta (ER- beta ) expressed in E. coli. |
Other Names | [Estrogen Receptor beta; Estrogen Receptor-beta], [Esr2; Esr2; Erb2; ERbeta; ER-beta; ERb2] |
Gene, Accession # | Gene ID: 25149, NCBI: NP_036886.1, UniProt: Q59IV8 |
Catalog # | MBS190148 |
Price | $425 |
Order / More Info | Estrogen Receptor- beta Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |