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Antigenic Specificity | Phospho-CDK1/CDC2 (Tyr15) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, ratpredicted: porcine, zebrafish, bovine, horse, rabbit, dog, chicken, Xenopus |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Peptide ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Phospho-CDK1/CDC2 (Tyr15) Antibody detects endogenous levels of CDK1/CDC2 only when phosphorylated at Tyr15. Description: Plays a key role in the control of the eukaryotic cell cycle by modulating the centrosome cycle as well as mitotic onset; promotes G2-M transition, and regulates G1 progress and G1-S transition via association with multiple interphase cyclins. Required in higher cells for entry into S-phase and mitosis. Phosphorylates PARVA/actopaxin, APC, AMPH, APC, BARD1, Bcl-xL/BCL2L1, BRCA2, CALD1, CASP8, CDC7, CDC20, CDC25A, CDC25C, CC2D1A, CENPA, CSNK2 proteins/CKII, FZR1/CDH1, CDK7, CEBPB, CHAMP1, DMD/dystrophin, EEF1 proteins/EF-1, EZH2, KIF11/EG5, EGFR, FANCG, FOS, GFAP, GOLGA2/GM130, GRASP1, UBE2A/hHR6A, HIST1H1 pr |
Immunogen | Immunogen: A synthesized peptide derived from human CDK1/CDC2 around the phosphorylation site of Tyr15. Tissue Specificity: Isoform 2 is found in breast cancer tissues. |
Other Names | [Cdc2 related protein kinase; cdc2-related protein kinase; CDC28; CDC2A; Cdk 2; CDK1; CDK2; CDK2_HUMAN; CDKN2; Cell devision kinase 2; Cell division protein kinase 2; Cyclin dependent kinase 2; cyclin dependent kinase 2-alpha; Cyclin-dependent kinase 2; kinase Cdc2; MPF; p33 protein kinase; p33(CDK2)] |
Gene, Accession # | [CDK1/CDC2], Gene ID: 983, NCBI: NP_001777.1, UniProt: P06493 |
Catalog # | MBS9610636 |
Price | $225, $280, $340 |
Order / More Info | Phospho-CDK1/CDC2 (Tyr15) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |