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Antigenic Specificity | Rat GSK3B / GSK3 Beta |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | bovine, human, mouse, rat |
Isotype | n/a |
Format | Protein A purified |
Size | 0.05 mg |
Concentration | 1 mg/ml |
Applications | Immunohistochemistry (IHC - Paraffin), Immunofluorescence (IF), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Glycogen Synthase Kinase 3 beta is a GSK-3 multisubstrate serine/threonine kinase that is associated with the canonical Wnt signaling pathway, which is involved in mammalian brain regionalization. Glycogen Synthase Kinase 3 beta has been implicated in Alzheimer's Disease, when improper phosphorylation of the microtubule-associated protein Tau results in the accumulation of neurofibrillary tangles. Two alternatively spliced isoforms have been observed. |
Immunogen | Immunogen Description: Synthetic peptide derived from the sequence of rat GSK3 beta, conjugated to KLH; sequence identical to human. |
Other Names | [GSK3B / GSK3 Beta IHC-plus; GSK3B; GSK-3 beta; GSK3 beta; GSK3beta; GSK3beta isoform; TPKI; GSK 3beta; Tau protein kinase I; ZGSK-3beta; Rat GSK3B; GSK3 Beta], [GSK3B; GSK3B; GSK-3 beta] |
Gene, Accession # | [GSK3B], Gene ID: 2932, NCBI: NP_002084.2, UniProt: P49841 |
Catalog # | MBS244854 |
Price | $530 |
Order / More Info | Rat GSK3B / GSK3 Beta Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |