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Antigenic Specificity | Human CD3 |
Clone | [4AOKT3] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2a |
Format | allophycocyanin (APC) conjugate |
Size | 50 tests, 100 tests |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS), Immunohistochemistry (IHC), Immunofluorescence (IF), Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | 4AOKT3 reacts with CD3, a 20-26 kDa molecule, which is expressed on all mature T lymphocytes (approximately 60-80% of normal human peripheral blood lymphocytes), NK-T cells and some thymocytes. CD3 associated with the T-cell receptor a/b or g/d dimer also plays a role in T-cell activation and signal transduction during antigen recognition.* CD3 mAb is used to count mature T cells in blood. |
Immunogen | n/a |
Other Names | [cd3; CD3gamma/delta; CD3gamma/delta] |
Gene, Accession # | [CD3], NCBI: CAA72995.1, UniProt: P79951 |
Catalog # | MBS8500601 |
Price | $280, $300 |
Order / More Info | Human CD3 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. 1.Ledbetter, J et al. (1981) J Exp Med 153:310-323. 2.Haynes, B et al. (1986) Leukocyte Typing II: Human T lymphocytes. New York: Sprimger-Verlag; 3-30. 3.Clevers H et al. (1988). Ann Rev Immunol 6: 629-662. 4.Barclay, N et al. (1993). The Leucocyte Factsbook. Academic Press. San Diego. |