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Antigenic Specificity | Phospho-JNK/SAPK(Thr183/Tyr185) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | ratpredicted: chicken, mouse, rat |
Isotype | n/a |
Format | unconjugated |
Size | 0.05 mL, 0.2 mL |
Concentration | 0.25 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 157-189 amino acids from human. Serine/threonine-protein kinase involved in various processes such as cell proliferation, differentiation, migration, transformation and programmed cell death. Extracellular stimuli such as proinflammatory cytokines or physical stress stimulate the stress-activated protein kinase/c-Jun N-terminal kinase (SAP/JNK) signaling pathway. In this cascade, two dual specificity kinases MAP2K4/MKK4 and MAP2K7/MKK7 phosphorylate and activate MAPK9/JNK2. In turn, MAPK9/JNK2 phosphorylates a number of transcription factors, primarily components of AP-1 such as JUN and ATF2 and thus regulates AP-1 transcriptional activity. In |
Immunogen | n/a |
Other Names | [Mitogen-activated protein kinase 9; MAP kinase 9; MAPK 9; 2.7.11.24; JNK-55; Stress-activated protein kinase 1a; SAPK1a; Stress-activated protein kinase JNK2; c-Jun N-terminal kinase 2; MAPK9; JNK2; PRKM9; SAPK1A; Purified Rabbit (Pab)] |
Gene, Accession # | [MAPK9], Gene ID: 5601, NCBI: P45984.2, UniProt: P45984 |
Catalog # | MBS9217365 |
Price | $165, $370 |
Order / More Info | Phospho-JNK/SAPK(Thr183/Tyr185) Antibody from MYBIOSOURCE INC. |
Product Specific References | Sluss H.K.,et al.Mol. Cell. Biol. 14:8376-8384(1994). Kallunki T.,et al.Genes Dev. 8:2996-3007(1994). Gupta S.,et al.EMBO J. 15:2760-2770(1996). Wang P.,et al.BMB Rep. 43:738-743(2010). Halleck A.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases. |