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Antigenic Specificity | ILK (Phospho-Ser246) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | epitope affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of ILK only when phosphorylated at serine 246. Transduction of extracellular matrix signals through integrins influences intracellular and extracellular functions, and appears to require interaction of integrin cytoplasmic domains with cellular proteins. Integrin-linked kinase (ILK), interacts with the cytoplasmic domain of beta-1 integrin. This gene encodes a serine/threonine protein kinase with 4 ankyrin-like repeats, which associates with the cytoplasmic domain of beta integrins and acts as a proximal receptor kinase regulating integrin-mediated signal transduction. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene.Hannigan G.E., Nature 379:91 |
Immunogen | Immunogen Type: Peptide-KLH Immunogen Description: Peptide sequence around phosphorylation site of Serine 246(I-F-S(p)-H-P) derived from Human ILK. |
Other Names | [ILK1; p59ILK; kinase ILK] |
Gene, Accession # | [ILK], Gene ID: 3611, NCBI: NP_001014794.1, UniProt: Q13418 |
Catalog # | MBS9403494 |
Price | $200, $255 |
Order / More Info | ILK (Phospho-Ser246) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |