Edit |   |
---|---|
Antigenic Specificity | SH3BP4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | SH3BP4 Antibody: SH3BP4 was initially isolated as a novel cDNA using differential display analysis using cultured human corneal fibroblasts. The protein contains three Asn-Pro-Phe (NPF) motifs, an SH3 domain, a PXXP motif, a bipartite nuclear targeting signal, and a tyrosine phosphorylation site. SH3BP4 has been shown to interact with specific endocytic proteins such as clathrin, dynamin, and the transferrin receptor (TfR) and localizes to TfR-containing coated pits and vesicles. It is thought to be involved in cargo-specific control of clathrin-mediated endocytosis, specifically controlling the internalization of TfR. At least two isoforms of SH3BP4 are known to exist. |
Immunogen | Immunogen: SH3BP4 antibody was raised against an 18 amino acid synthetic peptide from near the carboxy terminus of human SH3BP4. Buffer: SH3BP4 Antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [SH3BP4; TTP; BOG25; EHB10; TTP; SH3 domain-binding protein 4; EH-binding protein 10; SH3-domain binding protein 4], [SH3BP4; SH3BP4; TTP; BOG25; BOG25; EHB10; TTP] |
Gene, Accession # | [SH3BP4], Gene ID: 23677, NCBI: NP_055336, UniProt: Q9P0V3 |
Catalog # | MBS150940 |
Price | $375 |
Order / More Info | SH3BP4 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |