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Antigenic Specificity | M TLR4 (N-term), 25-55 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 2 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This Mouse TLR4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 25-55 amino acids from the N-terminal region of mouse TLR4. TLR4, a type I membrane protein that belongs to the Toll-like receptor family, cooperates with LY96 and CD14 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). It acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response TLR4 Belongs to the lipopolysaccharide (LPS) receptor, a multi-protein complex containing at least CD14, LY96 and TLR. TLR4 binds to LY96 via the extracellular domain, and to MyD88 and TIRAP via their respective TIR domains. The protein contains 19 leucine-rich (LRR) repeats, |
Immunogen | n/a |
Other Names | [Toll-like receptor 4; CD284; Tlr4; Lps] |
Gene, Accession # | [Tlr4], Gene ID: 21898, NCBI: NP_067272.1, UniProt: Q9QUK6 |
Catalog # | MBS9203360 |
Price | $165, $370 |
Order / More Info | M TLR4 (N-term), 25-55 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |