Edit |   |
---|---|
Antigenic Specificity | Galectin 10 Picoband |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: Eosinophil lysophospholipase is an enzyme that in humans is encoded by the CLC gene. Lysophospholipases are enzymes that act on biological membranes to regulate the multifunctional lysophospholipids. The protein encoded by this gene is a lysophospholipase expressed in eosinophils and basophils. It hydrolyzes lysophosphatidylcholine to glycerophosphocholine and a free fatty acid. This protein may possess carbohydrate or IgE-binding activities. It is both structurally and functionally related to the galectin family of beta-galactoside binding proteins. It may be associated with inflammation and some myeloid leukemias.Protein Function: Regulates immune responses through the recognition of cell-surface glycans. Essential for th |
Immunogen | Immunogen: E Coli-derived human Galectin 10 recombinant protein (Position: S2-R142). Subcellular Localization: Cytoplasm, cytosol. Tissue Specificity: Expressed abundantly in the bone marrow. Expressed exclusively by eosinophils and basophils. Not detected in monocytes and neutrophils. Expressed in CD25-positive regulatory T-cells (Treg) (at protein level). Found in intestinal tissue from patients with Celiac disease, expression is directly related to the histological grade of mucosal damage and |
Other Names | [Galectin-10; Charcot-Leyden crystal protein; CLC; Eosinophil lysophospholipase; Lysolecithin acylhydrolase; CLC; LGALS10; LGALS10A] |
Gene, Accession # | [Gal-10], NCBI: NP_001819.2, UniProt: Q05315 |
Catalog # | MBS1750622 |
Price | $280 |
Order / More Info | Galectin 10 Picoband Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |