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Antigenic Specificity | Phospho-VEGFR2 (Tyr-1214) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | Protein G purified |
Size | 0.1 mg |
Concentration | 1 mg/ml |
Applications | Western Blot (WB); Immunoblot; ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Polyclonal antibody to detect VEGFR2 (phospho-T1214) in human samples. Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA; VEGFC and VEGFD. Plays an essential role in the regulation of angiogenesis; vascular development; vascular permeability; and embryonic hematopoiesis. Promotes proliferation; survival; migration and differentiation of endothelial cells. Promotes reorganization of the actin cytoskeleton. Isoforms lacking a transmembrane domain; such as isoform 2 and isoform 3; may function as decoy receptors for VEGFA; VEGFC and/or VEGFD. Isoform 2 plays an important role as negative regulator of VEGFA- and VEGFC-mediated lymphangiogenesis by limiting the amount of free VEGFA and/or VEGFC and preventing their binding t |
Immunogen | Immunogen: Synthetic peptide |
Other Names | [VEGFR-2; FLK-1; KDR; CD309], [KDR; KDR; FLK1; CD309; VEGFR; VEGFR2; FLK1; VEGFR2; VEGFR-2; FLK-1; KDR] |
Gene, Accession # | [VEGFR2], Gene ID: 3791, NCBI: NP_002244.1, UniProt: P35968 |
Catalog # | MBS845921 |
Price | $345 |
Order / More Info | Phospho-VEGFR2 (Tyr-1214) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |