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Antigenic Specificity | Rad51 |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | n/a |
Isotype | IgG2b kappa |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | Immunoblot, Immunoprecipitation |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Anti-Rad51 [Murine MAb recognizes Rad51, a 37 kD protein that interacts with BRCA1 and BRCA2.]. This antibody recognizes human Rad51, a 37 kD protein that interacts with BRCA1. This interaction is important for tumor suppression. BRCA2 and Rad51 have also been shown to interact via the BRC repeats located with exon 11 of BRCA2. When these repeats are deleted, the interaction is lost, and cells become hypersensitive to DNA damage caused by methyl methanesulfonate (MMS). |
Immunogen | Antigen: GST fusion protein corresponding to full-length Rad51 (aa 1-338) of human Rad51 expressed in E. coli |
Other Names | [Rad51; Rad51], [RAD51; RAD51; RECA; BRCC5; HRAD51; RAD51A; HsRad51; HsT16930; RAD51A; RECA] |
Gene, Accession # | Gene ID: 5888, NCBI: CAG38796.1, UniProt: Q06609 |
Catalog # | MBS190396 |
Price | $425 |
Order / More Info | Rad51 Antibody from MYBIOSOURCE INC. |
Product Specific References | Shinohara, A et al. 1993. Nature Genetics 4: 239-243; Scully, R et al. 1997. Cell 88: 265-275; Chen, PL et al. 1998. PNAS (USA) 95: 5287-5292. For in vitro investigational use only. Not for use in therapeutic or diagnostic procedures. |