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Antigenic Specificity | Dcr-1 (Center), 1068-1097 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | C Elegan |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 2 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This Dcr-1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1068-1097 amino acids from the Central region of human Dcr-1. The Dcr-1 gene encodes a bidentate ribonuclease that is homologous to E. coli RNAse III. Dcr-1 is required both for RNA interference and for synthesis of small developmental RNAs. Dcr-1 interacts in vivo with RDE-4, a double-stranded RNA (dsRNA) binding protein required for RNAi that interacts with trigger dsRNAs and may function to deliver dsRNAs to Dcr-1 for endonucleolytic processing. |
Immunogen | n/a |
Other Names | [Endoribonuclease dcr-1; 3126-; dcr-1] |
Gene, Accession # | [dcr-1], Gene ID: 176138, NCBI: NP_498761.2, UniProt: P34529 |
Catalog # | MBS9202372 |
Price | $165, $370 |
Order / More Info | Dcr-1 (Center), 1068-1097 Antibody from MYBIOSOURCE INC. |
Product Specific References | Duchaine TF, et al. 2006. Cell 124:343-354. Denli AM, et al. 2004. Nature 432:231-235. Tabara H, et al. 2002. Cell 109:861-871. Grishok A, et al. 2001. Cell 106:23-34. Knight SW, et al. 2001. Science 293:2269-2271. |