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Antigenic Specificity | LCN2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Iron-trafficking protein involved in multiple processes such as apoptosis, innate immunity and renal development. Binds iron through association with 2,5-dihydroxybenzoic acid (2,5-DHBA), a siderophore that shares structural similarities with bacterial enterobactin, and delivers or removes iron from the cell, depending on the context. Iron-bound form (holo-24p3) is internalized following binding to the SLC22A17 (24p3R) receptor, leading to release of iron and subsequent increase of intracellular iron concentration. In contrast, association of the iron-free form (apo-24p3) with the SLC22A17 (24p3R) receptor is followed by association with an intracellular siderophore, iron chelation and iron transfer to the extracellular medium, thereby redu |
Immunogen | Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human LCN2 (NP 005555.2). |
Other Names | [p25; 24p3; MSFI; NGAL] |
Gene, Accession # | [LCN2], Gene ID: 3934, NCBI: CAG46889.1, UniProt: P80188 |
Catalog # | MBS8545193 |
Price | $280 |
Order / More Info | LCN2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |