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Antigenic Specificity | Human Cyclin-dependent kinase 9 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Protein kinase involved in the regulation of transcription. Member of the cyclin-dependent kinase pair (CDK9/cyclin-T) complex, also called positive transcription elongation factor b (P-TEFb), which facilitates the transition from abortive to productive elongation by phosphorylating the CTD (C-terminal domain) of the large subunit of RNA polymerase II (RNAP II) POLR2A, SUPT5H and RDBP. This complex is inactive when in the 7SK snRNP complex form. Phosphorylates EP300, MYOD1, RPB1/POLR2A and AR, and the negative elongation factors DSIF and NELF. Regulates cytokine inducible transcription networks by facilitating promoter recognition of target transcription factors (e.g. TNF-inducible RELA/p65 activation and IL-6-inducible STAT3 signaling). Pr |
Immunogen | Immunogen: Recombinant human Cyclin-dependent kinase 9 protein (153-372aa) Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-7331 / sc-484 / sc-8338 |
Other Names | [C-2K; Cell division cycle 2-like protein kinase 4; Cell division protein kinase 9; Serine/threonine-protein kinase PITALRE; Tat-associated kinase complex catalytic subunit; CDK9; CDC2L4; TAK], [CDK9; CDK9; TAK; C-2k; CTK1; CDC2L4; PITALRE; CDC2L4; TAK] |
Gene, Accession # | [CDK9], Gene ID: 1025, NCBI: NP_001252.1, UniProt: P50750 |
Catalog # | MBS1492848 |
Price | $120, $160 |
Order / More Info | Human Cyclin-dependent kinase 9 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |