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Antigenic Specificity | NHE3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | rat, mouse |
Isotype | n/a |
Format | APC-Cy7 conjugate |
Size | 0.1 mg |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Detects ~84 kDa. Sodium-hydrogen exchanger 3 (NHE3; Slc9a3) is an epithelial transport protein that carries out 1:1 exchange of Na+ and H+ across the plasma membrane. It is apically located in the proximal tubule of the kidney, the thick ascending limb of the kidney, and in small intestine (1). NHE3 is phosphorylated and regulated by multiple kinases including PKA, SGK1 and CK2. It can be phosphorylated by calyculin A, and dephosphorylated by PP1 catalytic subunit in vitro (2). |
Immunogen | Immunogen: Synthetic peptide mapping to AA 809 to 831 of rat sequence |
Other Names | [Rabbit Rat NHE3; Sodium/Hydrogen Exchanger 3; SLC9A3; Na+/H+ exchanger 3; isoform 3; Solute carrier family 9 member 3; NHE3MGC126720; MGC126718; solute carrier family 9 (sodium/hydrogen exchanger) member 3; NHE-3; Na(+)/H(+) exchanger 3; Sodium/hydrogen exchanger 3] |
Gene, Accession # | [NHE3], Gene ID: 24784, NCBI: NP_036786.1, UniProt: P26433 |
Catalog # | MBS8004481 |
Price | $525 |
Order / More Info | NHE3 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Kim G.H., Ecelbarger C.A., Knepper M.A. and Packer R.K. (1999) J Am Soc Nephrol. 10: 935-942. 2. Dynia D.W., Steinmetz A.G. and Kocinsky H.S. (2010) Am J Physoil Renal Physiol. 298(3): F745-F753. |