Edit |   |
---|---|
Antigenic Specificity | HNRNPA2B1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemisty (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: HNRNPA2B1 antibody detects endogenous levels of total HNRNPA2B1. Description: Heterogeneous nuclear ribonucleoprotein A2/B1 (hnRNP A2/B1) is a member of the hnRNP A/B family of related RNA binding proteins that bind pre-mRNA and are involved in the processing, metabolism and transport of nuclear pre-mRNA transcripts (1). Alternative splicing produces transcripts that encode two homologous hnRNP proteins, hnRNPA2 and hnRNPB1, from a single gene sequence (2). Studies demonstrate hnRNP A2/B1 splicing repression across multiple targets (3, 4) and that both proteins can bind and protect telomere repeat sequences from DNase digestion (5, 6). Altered expression of hnRNP B1 is seen in several forms of cancer, including squamous cell ca |
Immunogen | Immunogen: A synthesized peptide derived from human HNRNPA2B1 Subcellular Location: Nucleus > Nucleoplasm. Cytoplasm. Localized in cytoplasmic mRNP granules containing untranslated mRNAs. Component of ribonucleosomes. Predominantly nucleoplasmic, however isoform A2 is also found in the cytoplasm of cells in some tissues. Not found in the nucleolus. |
Other Names | [Heterogeneous nuclear ribonucleoprotein A2; Heterogeneous nuclear ribonucleoprotein A2/B1; Heterogeneous nuclear ribonucleoprotein B1; Heterogeneous nuclear ribonucleoproteins A2/B1; hnRNP A2/hnRNP B1; hnRNP A2; hnRNP A2/B1; hnRNP B1; hnRNP-A2; hnRNP-B1; hnRNPA2; Hnrnpa2b1; hnRNPB1; HNRPA2; HNRPA2B1; HNRPB1; Nuclear ribonucleoprotein particle A2 protein; RNP A2; RNP B1; RNP-A2; RNP-B1; RNPA2; RNPB1; ROA2_HUMAN; SNRPB1] |
Gene, Accession # | [HNRNPA2B1], Gene ID: 3181, NCBI: NP_002128.1, UniProt: P22626 |
Catalog # | MBS9606955 |
Price | $240, $280 |
Order / More Info | HNRNPA2B1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |