Edit |   |
---|---|
Antigenic Specificity | Human CD18 |
Clone | [IB4] |
Host Species | Mouse |
Reactive Species | human, primate, rabbit |
Isotype | IgG2a |
Format | phycoerythrin (RPE) conjugate |
Size | 120 tests |
Concentration | Volume: 0.2 ml |
Applications | Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Information: Human CD18 (beta2 integrin) forms a heterodimer with either alphaL, alphaM, or alphaX integrins (CD11a, b or c). CD11/CD18 heterodimeric molecules are involved with cell/cell and cell/extracellular adhesion in immune and inflammatory responses. Antibody IB4 recognizes the beta 2 integrin subunit (CD18) adhesion molecule of about 95 kd. Antibody IB4 blocks binding of ICAM-1 and ICAM-3 to LFA-1. |
Immunogen | Immunogen: Human peripheral blood monocytes |
Other Names | [human CD18 (beta2 Integrin)/R-PE], [cd18] |
Gene, Accession # | [CD18], Gene ID: 100136144, NCBI: NP_001117907.1 |
Catalog # | MBS666015 |
Price | $405 |
Order / More Info | Human CD18 Antibody from MYBIOSOURCE INC. |
Product Specific References | S.D. Wright et al, (1983) Proc Natl Acad Sci USA 80: 5699-5703. R.C. Landis et al, (1994) J Cell Biol 126: 529-537. M. Kaneko, et al, (1995) J Immunol 155: 2631-2641. A. Mazzone & G. Ricevuti, (1995) Haematologica 80: 161-175. |