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Antigenic Specificity | PKR |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 0.05 mg |
Concentration | 1 mg/ml |
Applications | Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | PKR is transcriptionally induced by interferon and activated by double-stranded RNA (dsRNA). PKR inhibits translation initiation through phosphorylation of the alpha subunit of the initiation factor eIF2 (eIF2alpha) and also controls the activation of several transcription factors such as NF-kappaB, p53 and the Stats. In addition, PKR mediates apoptosis induced by many different stimuli, such as LPS, TNF-alpha, viral infection and serum starvation. |
Immunogen | Immunogen: PKR antibody was raised in Rabbit using the peptide sequence around phosphorylation site of threonine 446 (K-R-T(p)-R-S) derived from Human PKR as the immunogen. |
Other Names | [Rabbit PKR; PKR; PKR; Phospho Thr446; Protein kinase R] |
Gene, Accession # | [PKR] |
Catalog # | MBS5309604 |
Price | $295 |
Order / More Info | PKR Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |