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Antigenic Specificity | CASP10 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Involved in the activation cascade of caspases responsible for apoptosis execution. Recruited to both Fas-and TNFR-1 receptors in a FADD dependent manner. May participate in the granzyme B apoptotic pathways. Cleaves and activates caspase-3,-4,-6,-7,-8, and-9. Hydrolyzes the small-molecule substrates, Tyr-Val-Ala-Asp-|-AMC and Asp-Glu-Val-Asp-|-AMC. |
Immunogen | Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 220-521 of human CASP10 (NP 116759.2). |
Other Names | [MCH4; ALPS2; FLICE2] |
Gene, Accession # | [CASP10], Gene ID: 843, NCBI: NP_001193453.1, UniProt: Q92851 |
Catalog # | MBS8543944 |
Price | $280 |
Order / More Info | CASP10 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |