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Antigenic Specificity | Human CAV1 / Caveolin 1 |
Clone | polyclonal |
Host Species | Goat |
Reactive Species | Gibbon, chimpanzee, gorilla, human, monkey. predicted reactivity: orangutan, guinea pig (at least 90% immunogen sequence identity) |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 0.05 mg |
Concentration | 0.5 mg/ml |
Applications | Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Human CAV1 / Caveolin. No cross-reactivity expected to Caveolin 2 and Caveolin 3. Caveolin 1 (CAV1) is the main component of the caveolae plasma membranes found in most cell types. Caveolin 1 functions as a membrane adaptor to link integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. CAV1 may also be a tumor suppressor gene and a negative regulator of the Ras-p42/44 MAP kinase cascade. |
Immunogen | Immunogen Description: Synthetic peptide C-DELSEKQVYDAH from an internal region of human CAV1 / Caveolin (NP_001744.2). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Baboon, Monkey, Marmoset (100%); Orangutan, Guinea pig (92%). |
Other Names | [CAV1 / Caveolin 1 (Internal) IHC-plus; CAV1; Caveolin-1; CGL3; CAV; MSTP085; VIP21; BSCL3; Human CAV1; Caveolin 1], [CAV1; CAV1; CGL3; PPH3; BSCL3; LCCNS; VIP21; MSTP085; CAV] |
Gene, Accession # | [CAV1], Gene ID: 857, NCBI: NP_001744.2, UniProt: Q03135 |
Catalog # | MBS240768 |
Price | $530 |
Order / More Info | Human CAV1 / Caveolin 1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |