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Antigenic Specificity | Phospho-EP300 (S1834) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | n/a |
Applications | Dot Blot (DB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This EP300 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S1834 of human EP300. This gene encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. It functions as histone acetyltransferase that regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation. It mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein. This gene has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF. Defects in this gene are a cause of |
Immunogen | n/a |
Other Names | [Histone acetyltransferase p300; p300 HAT; E1A-associated protein p300; EP300; P300] |
Gene, Accession # | [EP300], Gene ID: 2033, NCBI: NP_001420.2, UniProt: Q09472 |
Catalog # | MBS9213944 |
Price | $165, $370 |
Order / More Info | Phospho-EP300 (S1834) Antibody from MYBIOSOURCE INC. |
Product Specific References | Zhang, M., et al. J. Immunol. 185(7):3960-3969(2010) Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010) Vempati, R.K., et al. J. Biol. Chem. 285(37):28553-28564(2010) Reynoird, N., et al. EMBO J. 29(17):2943-2952(2010) Jang, E.R., et al. Biochem. Biophys. Res. Commun. 397(4):637-643(2010) |