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Antigenic Specificity | Phospho-GluR1 (S845) |
Clone | monoclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, ratpredicted reactivity: dog, chicken |
Isotype | n/a |
Format | affinity purified |
Size | 0.03 mg, 0.1 mg, 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L- glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate. |
Immunogen | Immunogen: A synthesized peptide derived from human GluR1 Subcellular Localization: Cell membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane, postsynaptic density. Cell projection, dendrite. Cell projection, dendritic spine. Interaction with CACNG2, CNIH2 and CNIH3 promotes cell surface expression. Tissue Specificity: |
Other Names | [Glutamate receptor 1; GluR-1; AMPA-selective glutamate receptor 1; GluR-A; GluR-K1; Glutamate receptor ionotropic; AMPA 1; GluA1; Gria1; Glur1] |
Gene, Accession # | [GluR1], Gene ID: 2890, NCBI: NP_000818.2, UniProt: P42261 |
Catalog # | MBS1750276 |
Price | $160, $340, $340 |
Order / More Info | Phospho-GluR1 (S845) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |