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Antigenic Specificity | IkBalpha |
Clone | [6A055] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 0.25 mg/ml |
Applications | Western Blot (WB), Immunoprecipitation (IP), Immunofluorescence (IF), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Background: NF-kB is silenced in the cytoplasm by an inhibitory protein, IkB. IkB proteins are phosphorylated by IkB kinase complex consisting of at least three proteins, IKK1/alpha, IKK2/beta, and IKK3/g. External stimuli such TNF-alpha or other cytokines results in phosphorylation and degradation of IkB releasing NF-kB dimers. NF-kB dimer subsequently translocates to the nucleus and activates target genes. Six members of IkB family members have been identified. One of the first gene induced following NF-kB activation is IkBalpha. |
Immunogen | Immunogen: Recombinant human IkBa |
Other Names | [IkappaBalpha; MAD3; MAD-3; IKBA; NFKBI; IKB-alpha; I-kappa-B-alpha], [NFKBIA; NFKBIA; IKBA; MAD-3; NFKBI; IKBA; MAD3; NFKBI; IkB-alpha; IkappaBalpha] |
Gene, Accession # | [IkBalpha], Gene ID: 4792, NCBI: NP_065390.1, UniProt: P25963 |
Catalog # | MBS840066 |
Price | $345 |
Order / More Info | IkBalpha Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |