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Antigenic Specificity | Phospho-AR-S650 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 1mg/ml |
Applications | Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using Phospho-AR-S650 antibody. The androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N-terminal domain, DNA-binding domain, and androgen-binding domain. The protein functions as a steroid-hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. This gene contains 2 polymorphic trinucleotide repeat segments that encode polyglutamine and polyglycine tracts in the N-terminal transactivation domain of its protein. Expansio |
Immunogen | Immunogen: A phospho specific peptide corresponding to residues surrounding S650 of human AR Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Other Names | n/a |
Gene, Accession # | [AR-S650] |
Catalog # | MBS4153045 |
Price | $510 |
Order / More Info | Phospho-AR-S650 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |