Edit |   |
---|---|
Antigenic Specificity | phospho-Rsk1 (Thr359/Ser363); |
Clone | [RM233] |
Host Species | Rabbit |
Reactive Species | human |
Isotype | IgG |
Format | Protein A purified |
Size | 0.05 mL |
Concentration | n/a |
Applications | Immunohistochemistry (IHC); Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit monoclonal antibody to detect phospho-Rsk1 (Thr359/Ser363) in human samples. The RSK (ribosomal S6 kinase) family comprises growth factor-regulated serine/threonine kinases; known also as p90 (rsk). RSK1 contains 2 nonidentical kinase catalytic domains and phosphorylates various substrates; including members of the mitogen-activated kinase (MAPK) signalling pathway. Moller described the cloning and characterization of 3 genes encoding RSKs; and HU1 (also named RPS6KA1; or RSK1) cDNA encodes a predicted 735-amino acid protein containing 2 distinct consensus ATP-binding site sequences. Northern blot and RNase protection analyses detected an approximately 3.5-kb HU1 transcript in lymphocytes; skeletal muscle; liver; and adipose tissue. |
Immunogen | Immunogen: A phospho-peptide corresponding to human phospho-Rsk1 (Thr359/Ser363) |
Other Names | [rsk-1; rsk 1; Active RSK1; RSK1; RSK; human RSK1; active kinase; active kinases; recombinant RSK1; recombinant RSK; kinase activity assay; protein kinase], [RPS6KA1] |
Gene, Accession # | [Rsk1], Gene ID: 6195, NCBI: NP_001006666.1, UniProt: Q15418 |
Catalog # | MBS846010 |
Price | $335 |
Order / More Info | phospho-Rsk1 (Thr359/Ser363); Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |