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Antigenic Specificity | CD105 Picoband |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | Add 0.2ml of distilled water will yield a concentration of 500ug/ml. |
Applications | ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: Endoglin (Osler-Rendu-Weber syndrome 1), CD105, is a type I membrane glycoprotein located on cell surfaces and is a part of the TGF beta receptor complex. Its gene is mapped to human chromosome 8. The protein consists of a homodimer of 180 kDA with disulfide links. It has been found on endothelial cells, activated macrophages, fibroblasts and smooth muscle cells. Endoglin has a role in the development of the cardiovascular system and in vascular remodeling and has been found to be elevated in pregnant women who subsequently develop preeclampsia.Protein Function: Major glycoprotein of vascular endothelium. Involved in the regulation of angiogenesis. May play a critical role in the binding of endothelial cells to integrins an |
Immunogen | Immunogen: E Coli-derived mouse CD105 recombinant protein (Position: E27-L226). Subcellular Localization: Membrane; Single-pass type I membrane protein. |
Other Names | [Endoglin; Cell surface MJ7/18 antigen; CD105; Eng; Edg] |
Gene, Accession # | [CD105], Gene ID: 13805, NCBI: NP_031958.2, UniProt: Q63961 |
Catalog # | MBS1750808 |
Price | $315 |
Order / More Info | CD105 Picoband Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |