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Antigenic Specificity | FAIM |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | FAIM Antibody: The susceptibility of primary splenic B cells to Fas-mediated apoptosis is regulated in a receptor-specific fashion. Terminal effectors of B cell Fas-resistance include the known anti-apoptotic proteins Bcl-xL, FLIP, and a recently identified protein termed FAIM. This molecule is broadly expressed in various tissues and exists in at least three isoforms. It is thought that resistance to Fas killing via increased expression of FAIM protects foreign antigen-specific B cells during interactions with FasL-bearing T cells whereas autoreactive B cells are deleted via Fas-dependent cytotoxicity. More recent results have indicated that FAIM interacts with both Trk and p75 neurotrophin receptor and may play a role in promoting neurite |
Immunogen | Immunogen: FAIM antibody was raised against a 14 amino acid synthetic peptide from near the carboxy terminus of human FAIM. Buffer: FAIM Antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [FAIM; FAIM1; FAIM1; Fas apoptotic inhibitory molecule 1; Fas apoptotic inhibitory molecule], [FAIM; FAIM; FAIM1; FAIM1] |
Gene, Accession # | [FAIM], Gene ID: 55179, NCBI: NP_060617, UniProt: Q9NVQ4 |
Catalog # | MBS150757 |
Price | $375 |
Order / More Info | FAIM Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |