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Antigenic Specificity | Glypican 3 (GPC3) (C-term), 529-560 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 1.4 |
Applications | Western Blot (WB), ELISA (EIA), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This Glypican 3 (GPC3) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 529-560 amino acids from the C-terminal region of human Glypican 3 (GPC3). GPC3 is a cell surface proteoglycan that bears heparan sulfate. This protein may be involved in the suppression/modulation of growth in the predominantly mesodermal tissues and organs, and may play a role in the modulation of IGF2 interactions with its receptor and thereby modulate its function. Members of the glypican-related integral membrane proteoglycan family contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol (GPI) linkage. These proteins may play a role in the control of cell division, growth regulation |
Immunogen | n/a |
Other Names | [Glypican-3; GTR2-2; Intestinal protein OCI-5; MXR7; Secreted glypican-3; GPC3; OCI5] |
Gene, Accession # | [GPC3], Gene ID: 2719, NCBI: NP_001158089.1, UniProt: P51654 |
Catalog # | MBS9209110 |
Price | $165, $370 |
Order / More Info | Glypican 3 (GPC3) (C-term), 529-560 Antibody from MYBIOSOURCE INC. |
Product Specific References | Nakatsura, T., et al., Clin. Cancer Res. 10(19):6612-6621 (2004). Boily, G., et al., Br. J. Cancer 90(8):1606-1611 (2004). Wichert, A., et al., Oncogene 23(4):945-955 (2004). Midorikawa, Y., et al., Int. J. Cancer 103(4):455-465 (2003). Sung, Y.K., et al., Cancer Sci. 94(3):259-262 (2003). |