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Antigenic Specificity | Human CD80 |
Clone | [MEM-233] |
Host Species | Mouse |
Reactive Species | n/a |
Isotype | IgG1 |
Format | no preservative |
Size | 1 mg |
Concentration | IgG concentration 1.0 mg/ml |
Applications | Flow cytometry (FC/FACS), Immunoprecipitation (IP), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Mouse anti Human CD80 antibody, clone MEM-233 recognizes human CD80, also known as B7-1, a ~60kDa type 1 trans-membrane protein expressed of macrophages, dendritic cells (Munro et al. 1994) and activated B-cells (Ranheim et al. 1993) CD80 is a member of the immunoglobulin superfamily having an extracellular domain bearing both a single Ig-v-like domain, a single Ig-c-like domain, a transmembrane sequence and a short cytoplasmic domain. Although the predicted molecular weight for human CD80 is ~33kDa, the presence of multiple (8) potential N-glycosylation sites (Chen et al. 1998) results in a migration corresponding to ~60kDa. Human CD80 along with CD86 act as co-stimulatory molecules and are both ligands for CD28 and CTLA-4 (Azuma et al. 19 |
Immunogen | n/a |
Other Names | [T-lymphocyte activation antigen CD80; T-lymphocyte activation antigen CD80; T-lymphocyte activation antigen CD80; B-lymphocyte activation antigen B7; CD80 antigen (CD28 antigen ligand 1, B7-1 antigen); CTLA-4 counter-receptor B7.1; activation B7-1 antigen; costimulatory factor CD80; costimulatory molecule variant IgV-CD80; CD80 molecule; Activation B7-1 antigen; BB1; CTLA-4 counter-receptor B7.1; B7; CD_antigen: CD80], [CD80; CD80; B7; BB1; B7-1; B7.1; LAB7; CD28LG; CD28LG1; CD28LG; CD28LG1; LAB7; B7] |
Gene, Accession # | [CD80], Gene ID: 941, NCBI: NP_005182.1, UniProt: P33681 |
Catalog # | MBS210200 |
Price | $675 |
Order / More Info | Human CD80 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |