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Antigenic Specificity | CD137/4-1BB |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse rat |
Isotype | n/a |
Format | unconjugated |
Size | 0.05 mL |
Concentration | n/a |
Applications | Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Polyclonal antibody to detect CD137/4-1BB in human; mouse and rat samples. 4-1BB is also known as CD137; tumor necrosis factor receptor superfamily member 9 (TNFRSF9); induced by lymphocyte activation (ILA); is a co-stimulatory molecule of the tumor necrosis factor (TNF) receptor superfamily. CD137 can be expressed by activated T cells; but to a larger extent on CD8 than on CD4 T cells. In addition; CD137 expression is found on dendritic cells; follicular dendritic cells; natural killer cells; granulocytes and cells of blood vessel walls at sites of inflammation. The best characterized activity of CD137 is its costimulatory activity for activated T cells. Crosslinking of CD137 enhances T cell proliferation; IL-2 secretion survival and cytol |
Immunogen | n/a |
Other Names | [ILA; 4-1BB; CD137; CDw137; Tumor necrosis factor receptor superfamily member 9; 4-1BB ligand receptor; T-cell antigen 4-1BB homolog; T-cell antigen ILA; TNFRSF9], [TNFRSF9] |
Gene, Accession # | [CD137/4-1BB], Gene ID: 3604, NCBI: NP_001552.2, UniProt: Q07011 |
Catalog # | MBS845965 |
Price | $365 |
Order / More Info | CD137/4-1BB Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |