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Antigenic Specificity | DRD4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: DRD4 antibody detects endogenous levels of total DRD4. Function: Dopamine receptor responsible for neuronal signaling in the mesolimbic system of the brain, an area of the brain that regulates emotion and complex behavior. Activated by dopamine, but also by epinephrine and norepinephrine, and by numerous synthetic agonists and drugs (PubMed:9003072, PubMed:16423344, PubMed:27659709, PubMed:29051383). Agonist binding triggers signaling via G proteins that inhibit adenylyl cyclase (PubMed:7512953, PubMed:7643093, PubMed:16423344, PubMed:27659709, PubMed:29051383). Modulates the circadian rhythm of contrast sensitivity by regulating the rhythmic expression of NPAS2 in the retinal ganglion cells (By similarity).Subunit Structur |
Immunogen | Immunogen: A synthesized peptide Subcellular Location: Cell Membrane Tissue Specificity: Highly expressed in retina. Detected at much lower levels in brain, in amygdala, thalamus, hypothalamus, cerebellum and pituitary. Predicted Cross Reactivity: Pig, Bovine, Horse, Chicken, Xenopus Similarity: Pig (100%), Bovine (100%), Horse (100%), Chicken (91%), Xenopus (91%) |
Other Names | [D(2C) dopamine receptor; D(4) dopamine receptor (D(2C) dopamine receptor).; D(4) dopamine receptor; D4 dopamine receptor; D4DR; Dopamine D4 receptor; DRD 4; Drd4; DRD4_HUMAN] |
Gene, Accession # | [DRD4], Gene ID: 1815, NCBI: NP_000788.2, UniProt: P21917 |
Catalog # | MBS9606318 |
Price | $240, $280 |
Order / More Info | DRD4 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |