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Antigenic Specificity | BACE1B (Center) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | unconjugated |
Size | 0.08 mL, 0.4 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin, ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This BACE1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 169-198 amino acids from the Central region of human BACE1B. Description: Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein (APP) by two proteases, one of which is the BACE1. The encoded protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease that is found mainly in the Golgi. Background: Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, betwe |
Immunogen | n/a |
Other Names | [Beta-secretase 1; Aspartyl protease 2; ASP2; Asp 2; Beta-site amyloid precursor protein cleaving enzyme 1; Beta-site APP cleaving enzyme 1; Memapsin-2; Membrane-associated aspartic protease 2; BACE1; BACE; KIAA1149] |
Gene, Accession # | [BACE1], Gene ID: 23621, NCBI: NP_001193978.1, UniProt: P56817 |
Catalog # | MBS9217128 |
Price | $165, $370 |
Order / More Info | BACE1B (Center) Antibody from MYBIOSOURCE INC. |
Product Specific References | Christensen, M.A., et al., Mol. Cell. Biol. 24 (2):865-874 (2004). Lichtenthaler, S.F., et al., J. Biol. Chem. 278 (49):48713-48719 (2003). Hussain, I., et al., J. Biol. Chem. 278 (38):36264-36268 (2003). Basi, G., et al., J. Biol. Chem. 278 (34):31512-31520 (2003). Clarimon, J., et al., J. Neurol. 250 (8):956-961 (2003). |