Edit |   |
---|---|
Antigenic Specificity | Phospho-MAPK14-Y322 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK14 is one of the four p38 MAPKs which play an important role in the cascades of cellular responses evoked by extracellular stimuli such as proinflammatory cytokines or physical stress leading to direct activation of transcription factors. Accordingly, p38 MAPKs phosphorylate a broad range of proteins and it has been estimated that they may have approximately 200 to 300 substrates each. Some of the targets are downstream kinases which are activated through phosphorylation and further phosphorylate additional targets. RPS6KA5/MSK1 and RPS6KA4/MSK2 can directly phosphorylate and activate transcription factors such as CREB1, ATF1, the |
Immunogen | Immunogen: A phospho specific peptide corresponding to residues surrounding Y322 of human MAPK14 |
Other Names | [RK; p38; CSBP; EXIP; Mxi2; CSBP1; CSBP2; CSPB1; PRKM14; PRKM15; SAPK2A; p38ALPHA] |
Gene, Accession # | [MAPK14], Gene ID: 1432, NCBI: NP_001306.1, UniProt: Q16539 |
Catalog # | MBS8550577 |
Price | $280 |
Order / More Info | Phospho-MAPK14-Y322 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |