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Antigenic Specificity | Human c-Myc |
Clone | [NYRhc-myc] |
Host Species | Mouse |
Reactive Species | n/a |
Isotype | IgG1 |
Format | Protein A purified |
Size | 0.5 mg, 1 mg |
Concentration | 1mg/ml in PBS (after reconstitution). |
Applications | ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Introduction: c-Myc is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of c-Myc have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the norma |
Immunogen | Immunogen: synthetic peptides. |
Other Names | [c-myc; c-myc, Mouse Human; MYC; CMYC; C-MYS; V-MYC; P64], [c-myc] |
Gene, Accession # | [c-Myc], NCBI: Q6LBK7 |
Catalog # | MBS140100 |
Price | $305, $455 |
Order / More Info | Human c-Myc Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |