NCSTN Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityNCSTN
Clonepolyclonal
Host SpeciesRabbit
Reactive Speciesmouse, rat
Isotypen/a
Formataffinity purified
Size0.06 mL, 0.12 mL, 0.2 mL
Concentration1 mg/mL
ApplicationsWestern Blot (WB)
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DescriptionThis gene encodes a type I transmembrane glycoprotein that is an integral component of the multimeric gamma-secretase complex. The encoded protein cleaves integral membrane proteins, including Notch receptors and beta-amyloid precursor protein, and may be a stabilizing cofactor required for gamma-secretase complex assembly. The cleavage of beta-amyloid precursor protein yields amyloid beta peptide, the main component of the neuritic plaque and the hallmark lesion in the brains of patients with Alzheimer's disease; however, the nature of the encoded protein's role in Alzheimer's disease is not known for certain. Mutations in this gene are associated with familial acne inversa. A pseudogene of this gene is present on chromosome 21. Alternativ
ImmunogenImmunogen: Recombinant protein of human NCSTN
Other Names[Anterior pharynx defective 2; APH 2; APH2; ATAG1874; KIAA0253; Ncstn; NCT; NICA; Nicastrin; RP11 517F10.1; RP11517F101]
Gene, Accession #[NCSTN], Gene ID: 23385, NCBI: NP_001277113.1, UniProt: Q92542
Catalog #MBS2555391
Price$150, $225, $360
Order / More InfoNCSTN Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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