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Antigenic Specificity | BAP31 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Bap31 and the related protein Bap29 are endoplasmic reticulum (ER) and ER-vesicle membrane proteins and members of the B-cell receptor-associated protein family. These two proteins are highly homologous and can form homo- and heterodimers. Bap31 is thought to be involved in the intracellular trafficking of several molecules such as MHC Class I molecules and CD11b/CD18. Bap31 may also play a role in the initiation of ER stress-induced apoptosis through its association with caspase-8 via a death effector domain in its cytoplasmic tail, possibly through the promotion of membrane fragmentation and the release of cytochrome c from mitochondria. Bap31 itself contains two caspase cleavage sites and is cleaved during apoptosis. The p20 fragment of |
Immunogen | Immunogen Type: Peptide Immunogen Description: Raised against a 17 amino acid peptide from near the center of human BAP31. |
Other Names | [B cell receptor-associated protein 31 BCR associated protein 31] |
Gene, Accession # | [BAP31], Gene ID: 10134, NCBI: NP_005736 |
Catalog # | MBS9402417 |
Price | $320 |
Order / More Info | BAP31 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |