HSPA8 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHSPA8
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatimmunogen affinity purified
Size0.05 mL, 0.1 mL
Concentration1.0 mg/ml
ApplicationsWestern Blot (WB)
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DescriptionThe antibody detects endogenous levels of total HSPA8 protein. Acts as a repressor of transcriptional activation. Inhibits the transcriptional coactivator activity of CITED1 on Smad-mediated transcription. Chaperone. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. May have a scaffolding role in the spliceosome assembly as it contacts all other components of the core complex. Binds bacterial lipopolysaccharide (LPS) et mediates LPS-induced inflammatory response, including TNF secretion by monocytes.Muraki T., Mol. Pharmacol. 58:1257-1263(2000).Quadroni M., Submitted (MAR-2009).Keith W.N., Submitted (JAN-2010).
ImmunogenImmunogen Type: Peptide Immunogen Description: Synthesized peptide derived from internal of human HSPA8.
Other Names[BRODL; bromodomain and WD repeat domain containing 3; FLJ38568]
Gene, Accession #[HSPA8], Gene ID: 3312, NCBI: NP_006588.1, UniProt: P11142
Catalog #MBS9411534
Price$200, $255
Order / More InfoHSPA8 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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