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Antigenic Specificity | HSPA8 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total HSPA8 protein. Acts as a repressor of transcriptional activation. Inhibits the transcriptional coactivator activity of CITED1 on Smad-mediated transcription. Chaperone. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. May have a scaffolding role in the spliceosome assembly as it contacts all other components of the core complex. Binds bacterial lipopolysaccharide (LPS) et mediates LPS-induced inflammatory response, including TNF secretion by monocytes.Muraki T., Mol. Pharmacol. 58:1257-1263(2000).Quadroni M., Submitted (MAR-2009).Keith W.N., Submitted (JAN-2010). |
Immunogen | Immunogen Type: Peptide Immunogen Description: Synthesized peptide derived from internal of human HSPA8. |
Other Names | [BRODL; bromodomain and WD repeat domain containing 3; FLJ38568] |
Gene, Accession # | [HSPA8], Gene ID: 3312, NCBI: NP_006588.1, UniProt: P11142 |
Catalog # | MBS9411534 |
Price | $200, $255 |
Order / More Info | HSPA8 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |