CD86 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCD86
Clone[24F]
Host SpeciesMouse
Reactive Speciesrat
IsotypeIgG1 kappa
Formatfluorescein (FITC) conjugate
Size0.05 mg, 0.1 mg
Concentration500 ug/ml
ApplicationsFlow Cytometry (FC/FACS)
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DescriptionThe 24F monoclonal antibody reacts with rat CD86, an ~90 kDa surface receptor, also known as B7-2. CD86 and CD80 are members of the B7 family of costimulatory molecules. CD86 is expressed by germinal center B cells and at low levels on macrophages, dendritic cells and non-lymphoid cells in the thymus. Its expression is upregulated on B cells through a variety of surface stimuli including LPS. In addition to CD80, CD86 is a counter-receptor for the T cell surface molecules CD28 and CD152. The interaction of CD86 with its ligands plays a critical role in T-B crosstalk, T cell costimulation, autoantibody production and Th2-mediated Ig production. The kinetics of upregulation of CD86 upon stimulation supports its major contribution during the p
Immunogenn/a
Other Names[Mouse CD86 (FITC); CD86; CD86; CD 86; CD-86; CD86; CD-86; CD 86; B72]
Gene, Accession #[CD86], Gene ID: 942, NCBI: CAG46642.1, UniProt: P42081
Catalog #MBS5309327
Price$215, $325
Order / More InfoCD86 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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