Cyclin D1 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Cyclin D1 |
| Clone | monoclonal |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG2a |
| Format | affinity purified |
| Size | 0.1 mg |
| Concentration | 100ug/100ul |
| Applications | Western Blot (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: Anti-Cyclin D1 Antibody recognizes human Cyclin D1. The DMITF1 encodes a transcription factor that contains a cyclin-D binding domain. Expression of this gene is frequently reduced in 40% of human non-small-cell lung carcinomas due to hemizygous gene deletion, strongly suggesting that this locus is haploinsufficient for tumor suppression. The Cyclin D1 is induced by the oncogenic Ras signalling pathway and functions as a tumor suppressor by activating the transcription of ARF to arrest cell growth or induce apoptosis. Other diseases related with the DMITF1 gene include parathyroid adenomas and mantle-cell lymphoma (MCL). The Anti-Cyclin D1 Antibody is a useful tool in cancer research particularly in studying oncogenesis. |
| Immunogen | Immunogen: Recombinant protein corresponding to human Cyclin D1 Storage Buffer: PBS, pH 7.4 with 0.05% sodium azide |
| Other Names | [cyclin D1, partial; Cyclin D1; Cyclin D1] |
| Gene, Accession # | NCBI: CAA54800.1, UniProt: Q9H014 |
| Catalog # | MBS4152812 |
| Price | $260 |
| Order / More Info | Cyclin D1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
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