Edit |   |
---|---|
Antigenic Specificity | TRPV1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | n/a |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The transient receptor potential cation channel, subfamily V, member 1 (TRPV1), also known as the capsaicin receptor is a protein which in humans is encoded by the TRPV1 gene.1, 2 TRPV1 (also called Vanilloid receptor type 1) is a ligand-gated nonselective cation channel that is considered to be an important integrator of various pain stimuli such as endogenous lipids, capsaicin, heat, and low pH. In addition to expression in primary afferents, TRPV1 is also expressed in the CNS. Cui M et al. (2006) demonstrate that TRPV1 receptors in the CNS play an important role in pain mediated by central sensitization. And the significant CNS penetration is necessary for a TRPV1 antagonist to produce broad-spectrum analgesia.3 And TRPV1 also participat |
Immunogen | Immunogen: TRPV1 antibody was raised in Rabbit using a synthetic peptide corresponding to a sequence at the N-terminal of human TRPV1, identical to the related rat and Rabbit sequences, as the immunogen |
Other Names | [Affinity Purified Rabbit TRPV1; TRPV1; TRPV1; TRPV 1; TRPV-1; TRPV-1; TRPV 1; TRPV1] |
Gene, Accession # | [TRPV1], Gene ID: 83810, UniProt: O35433 |
Catalog # | MBS5312657 |
Price | $345 |
Order / More Info | TRPV1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |