Edit |   |
Antigenic Specificity | ITA6 |
Clone | [129CT49.6.5] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1,kappa |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.42 |
Applications | Immunofluorescence (IF), ELISA (EIA), Western Blot (WB), Flow Cytometry (FC/FACS), Immunohistochemistry-Paraffin (IHC-P) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: ITA6 recombinant protein is used to produce this monoclonal antibody. The ITGA6 protein product is the integrin alpha chain alpha 6. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. For example, alpha 6 may combine with beta 4 in the integrin referred to as TSP180, or with beta 1 in the integrin VLA-6. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. Two transcript variants encoding different isoforms have been found for this gene. |
Immunogen | n/a |
Other Names | [Integrin alpha-6; CD49 antigen-like family member F; VLA-6; CD49f; Integrin alpha-6 heavy chain; Integrin alpha-6 light chain; Processed integrin alpha-6; Alpha6p; ITGA6] |
Gene, Accession # | [ITGA6], Gene ID: 3655, NCBI: NP_000201.2, UniProt: P23229 |
Catalog # | MBS9200194 |
Price | $165, $370 |
Order / More Info | ITA6 Antibody from MYBIOSOURCE INC. |
Product Specific References | Evaluation of candidate stromal epithelial cross-talk genes identifies association between risk of serous ovarian cancer and TERT, a cancer susceptibility hot-spot. Johnatty SE, et al. PLoS Genet, 2010 Jul 8. PMID 20628624. Prostate cancer risk-associated variants reported from genome-wide association studies: Meta-analysis and their contribution to genetic Variation. Kim ST, et al. Prostate, 2010 Jun 16. PMID 20564319. alpha6-integrin subunit plays a major role in the proangiogenic properties of endothelial progenitor cells. Bouvard C, et al. Arterioscler Thromb Vasc Biol, 2010 Aug. PMID 20508204. Common polymorphisms in ITGA2, PON1 and THBS2 are associated with coronary atherosclerosis in a candidate gene association study of the Chinese Han population. Wang Y, et al. J Hum Genet, 2010 Aug. PMID 20485444. Usage of heparan sulfate, integrins, and FAK in HPV16 infection. Abban CY, et al. Virology, 2010 Jul 20. PMID 20441998. |