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Antigenic Specificity | Human LTbR (Lymphotoxin beta Receptor) |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1k |
Format | Protein A purified |
Size | 0.1 mL |
Concentration | 1ug/ul |
Applications | Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Antibody ANCLTR2 binds to human LTbR present on U-937 cell surface, and to recombinant LTbR-muIg in EIA. mAb name/Clone: ANCLTR2/9E2 Human Lymphotoxin beta receptor (LTbR, TNFSF3) is a member of the TNF receptor superfamily with similarilty to CD120a(TNFR1) and CD120b(TNFR2). It is a expressed mainly on non lymphoid tissues(1) and appears to have an important role in secondary lymphoid organ development(5). Suppression of LTbR signaling can alleviate autoimmunity(2) or exasperate mycobacterial infection(6). Its ligands include Ltab2 and LIGHT. In mice, LTbR signaling is important for development and function of HEV(2), Dendritic cells(3), and Mast cells(4). |
Immunogen | Immunogen: Recombinant LTbR-muIg |
Other Names | [Lymphotoxin beta receptor, partial; tumor necrosis factor receptor superfamily member 3; lymphotoxin beta receptor] |
Gene, Accession # | [LTbR], Gene ID: 4055 |
Catalog # | MBS4159622 |
Price | $540 |
Order / More Info | Human LTbR (Lymphotoxin beta Receptor) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |